High-Throughput Screening (HTS) Market, valued at US$25.7 billion in 2023, is forecasted to grow at a robust CAGR of 11.8%, reaching US$28.8 billion in 2024 and an impressive US$50.2 billion by 2029. The comprehensive research encompasses an exhaustive examination of industry trends, meticulous pricing analysis, patent scrutiny, insights derived from conferences and webinars, identification of key stakeholders, and a nuanced understanding of market purchasing dynamics.
There has been a substantial increase in the R&D funding which is supporting the innovation efforts for the development of novel therapeutics. Therefore, increasing drug discovery initiatives are leading to the growing adoption of high throughput screening (HTS) offerings and technologies. However, the high costs associated with the HTS instruments are anticipated to hinder market growth.
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The consumables segment dominated the high throughput screening industry by offerings:
Based on offerings, the high throughput screening market is segmented into consumables, instruments, services, and software. The consumables segment accounted for the largest share of the global high-throughput screening market in 2023. The large share of the segment can be attributed to factors such as the requirement for a wide range of reagents and kits in the HTS workflow, the need for the repeated purchase of consumables, unlike instruments, and a favorable drug discovery research funding/ investment scenario.
The Asia Pacific region is expected to register the fastest growth in the high throughput screening industry during the forecast period.
The Asia Pacific region is expected to account for the fastest-growing region of the high throughput screening market during the forecast period. The Asia Pacific region has a diverse pool of patient population, which adopts a wide range of therapeutics. This drives the need for the development and commercialization of novel therapeutics in the region. Thus, this in turn, supports the growth of the market in the region. Additionally, the region has a strong presence of key global pharmaceutical and biotechnology companies involved in innovation in the pharmaceutical industry.
North America was the largest regional market for high-throughput screening in 2022.
Geographically, the high-throughput screening market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa. In 2022, North America accounted for the largest share of the high-throughput screening market, followed by Europe and the Asia Pacific. The large share of North America in the global market is attributed to the increasing prevalence of diseases, rising pharmaceutical R&D expenditure, and the presence of major players in the region are factors driving the growth of the HTS market in this region.
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High-Throughput Screening (HTS) Market Dynamics:
Drivers:
- The growing adoption of open innovation models in pharmaceutical & biotechnology companies
- Government funding and venture capital investments
- Increasing R&D spending
- Technological advancements in the HTS market
Restraints:
- The capital-intensive nature of HTS instruments
- Complexities in assay development
Opportunities:
- Emerging markets
- Growing applications in stem cell research
Challenges:
- The dearth of skilled operators
Key Market Players:
Key players in the high throughput screening market include Thermo Fisher Scientific Inc. (US), Agilent Technologies, Inc. (US), Merck KGaA (Germany), Danaher Corporation (US), Revvity, Inc. (US), Tecan Group Ltd. (Switzerland), Bio-Rad Laboratories, Inc. (US), Corning Incorporated (US), Mettler-Toledo International Inc. (US), Lonza (Switzerland), Waters Corporation (US), Sartorius AG (Germany), Eppendorf SE (Germany), Porvair PLC (UK), Greiner AG (Austria), Charles River Laboratories (US), Eurofins Scientific (Europe), Hamilton Company (US), Aurora Biomed Inc. (Canada), Gilson Incorporated (US), Brand GmbH+Co KG (Germany), BMG Labtech GmbH (Germany), DIANA Biotechnologies, A.S. (Czech Republic), Creative Biolabs. (US), HighRes Biosolutions. (US), Biomat Srl (Italy), AXXAM S.p.A. (Italy), Sygnature Discovery Limited (UK), and Crown Bioscience (US).
Recent Developments:
- In October 2023, Revvity Inc. (US), collaborated with SCIEX, a subsidiary of Danaher Corporation (US), to develop mass spectrometry solutions for newborn screening.
- In May 2024, Bio-Rad Laboratories, Inc. (US) launched three new StarBright Red Dyes—StarBright Red 715, 775, and 815—providing greater choice and flexibility in conventional and full-spectrum multicolor flow cytometry panels.
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High-Throughput Screening (HTS) Market Advantages:
- Accelerated Drug Discovery: High-throughput screening (HTS) expedites the drug discovery process by quickly screening a large number of compounds against specific targets. This speed enables researchers to identify potential drug candidates more rapidly, reducing the time and resources required for drug development.
- Increased Efficiency: HTS employs automation, robotics, and advanced technologies, resulting in enhanced efficiency and productivity. The automated systems can handle multiple samples simultaneously, reducing manual labor and minimizing human error. This streamlines the screening process, allowing researchers to screen thousands or even millions of compounds in a shorter time frame.
- Comprehensive Screening: HTS offers a systematic and comprehensive approach to screening compounds. By screening a vast library of compounds, including diverse chemical structures and natural products, HTS increases the likelihood of identifying compounds with desired biological activities. This broad exploration expands the possibilities for discovering novel drug candidates.
- Target-specific Screening: HTS enables researchers to target specific molecular pathways or cellular functions, allowing for more focused screening. This approach increases the chances of identifying compounds that interact with the desired targets, leading to the discovery of potential therapeutics with specific mechanisms of action.
- Cost-effectiveness: Although the initial setup costs of HTS can be significant, the long-term benefits often outweigh the investment. By streamlining the drug discovery process, HTS reduces costs associated with labor, reagents, and time. This cost-effectiveness makes HTS an attractive option for pharmaceutical companies and research institutions aiming to optimize their resources.
- Innovation and Exploration: HTS fosters innovation by enabling researchers to explore vast chemical libraries and screen for various therapeutic targets. This approach encourages the discovery of new drug classes and expands the possibilities for developing treatments for challenging diseases.
- Translational Research: HTS facilitates the translation of basic research findings into practical applications. By efficiently identifying potential drug candidates, HTS bridges the gap between academic research and clinical development, paving the way for the development of new treatments and therapies.
- Beyond Pharmaceutical Applications: HTS has expanded beyond traditional drug discovery and found applications in other fields such as personalized medicine and agricultural research. In personalized medicine, HTS allows for the screening of patient samples to identify tailored treatment options. In agriculture, HTS enables the screening of compounds for crop improvement and disease resistance, optimizing agricultural practices.
In summary, the advantages of the HTS market lie in its ability to accelerate drug discovery, increase efficiency, facilitate comprehensive and targeted screening, offer cost-effectiveness, drive innovation, support translational research, and extend its applications beyond pharmaceuticals. These advantages position HTS as a valuable tool for advancing scientific research and improving human health.
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